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Helicobacter pylori infection was reported to affect gastric acid secretion. We investigated the heartburn symptoms of patients with gastro-oesophageal reflux disease during sequential treatment with 40mg of famotidine or 15mg of lansoprazole to clarify whether H. pylori infection influences symptomatic response to anti-secretory therapy.The subjects were 33 gastro-oesophageal reflux disease patients,...