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Packaging of viral genomes into their respective capsids requires partial neutralization of the highly negatively charged RNA or DNA. Many viruses, including the Microviridae bacteriophages φX174, G4, and α3, have solved this problem by coding for a highly positively charged nucleic acid-binding protein that is packaged along with the genome. The φX174 DNA-binding protein, J, is 13 amino acid residues...