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Modulatory effects of erythropoietin (EPO) on the cellular and humoral compartments of the immune system have been described; however, the mechanism of action by which EPO affects the lymphocyte number and functions has yet to be elucidated. Because no EPO receptors (EPO–R) could be detected on lymphocytes, we searched for cells that might express the EPO–R and thereby mediate these immunomodulatory...