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This paper reports on the activity of bovine immunoglobulins IgG and IgG1 directed towards 19 microbial pathogens in an early milk concentrate from non-immunised cows and in a hyperimmune milk using an ELISA technique. Both products contained IgG and IgG1 which bound to all the microbial antigens tested. The early milk concentrate demonstrated a significantly higher IgG and IgG1 antibody titre (P<0...