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Fibroblast growth factors are known to influence the growth and differentiation of cultured cells derived from the chick retina. The fibroblast growth factors can interact with a family of at least four closely related receptor kinases. To find a correlation between the presence of fibroblast growth factor receptors and eye development, the patterns of expression of transcripts encoding the type...
This paper describes an experimental model of choroidal neovascularisation in the minipig, induced by recombinant human basic fibroblast growth factor (bFGF) infused into the suprachoroidal space via a catheter attached to an osmotic minipump. The experiment was carried out on 32 eyes. There were 17 eyes infused with bFGF (the study group), 10 controls (4 received phosphate buffered saline, 2 heat...