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A rapid, selective and accurate method for stability determination of 3-chloro-N-chloro-N-(3,4-dimethyl-5-isoxazolyl)-4-amine-1,2-naphthoquinone (1b) in the presence of its degradation products by using second derivative UV spectrophotometry was developed. The validity of this method was proved using synthetic mixtures of the intact drug with its decomposition products and by statistical analysis...