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An updated image sensor to be used in a miniature microscope system for recording brain activity over a wide cortical area (4–9 mm2) is presented. The image sensor is a 100 × 100 pixel array fabricated in bulk CMOS process. The sensor also contains a 10-bit ADC and two input channels to measure other physiological signals concurrently with the optical data. Another feature of the image sensor is the...
In this paper we present a rodent head-mountable, fully self contained imaging device that is capable of recording high speed fluorescent signals from genetically-encoded probes or voltage sensitive dyes. This device enables the study of neuronal activity in awake and mobile animals during more natural behaviors without the stress and suppression of anesthesia and restraints. The device is a fully...
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