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In rats, the administration of oil submitted to high temperatures is teratogenic. To understand the mechanisms involved, the clastogenic and cytotoxic effects were studied respectively in lymphocytes, hepatocytes (HepG2) and in human umbilical vein endothelial cells (HUVEC) cultured with a water extract obtained from heated oil (HO). In lymphocytes incubated with HO containing 0.075 or 0.15μM of thiobarbituric...