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Sorafenib, is a relatively new cytostatic drug approved for the treatment of renal cell and hepatocellular carcinoma. The development of new sorafenib analogues offers the possibility of generating structures of increased potency. To this end, a series of arylated-diphenylurea analogues 17–31 were synthesized via Suzuki-Miyaura coupling reaction, related to sorafenib by treatment of three diarylureas...