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The occurrence of an unexpected side effect following the use of Maloprim ( R) (pyrimethamine/dapsone) for malaria chemosuppression in 3-59 months old children in Sierra Leone is reported. As part of a trial of chemoprophylaxis and insecticide-impregnated bed nets, 2000 children received either Maloprim ( R) or placebo; 4% of children who received Maloprim ( R) fortnightly...