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Recent studies have shown that the CD1 family of proteins present various glycolipid antigens to subsets of T cells. CD1d is expressed on human intestinal epithelial cells (IEC) and exists in two biochemical forms: 37-kDa, β2-microglobulin (β2m) independent, nonglycosylated, and 47-kDa, β2m dependent, glycosylated forms. The biosynthetic pathways and the mechanisms of generation of these two biochemically...
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