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New Findings
What is the central question of this study?
The current literature indicates that oxidative stress plays a major role in iron overload. Although exercise is a well‐established approach to treat/prevent cardiovascular diseases, its effects on iron overload are not known.
What is the main finding and its importance?
Moderate‐intensity aerobic training had benefits in a rodent model...
Although iron excess is toxic to the vasculature and even that pulmonary hypertension has been reported in this scenario, the role of iron overload per se remains to be clarified. This study aimed to test the effects of chronic iron-overload in rats on the morphophysiology of resistance pulmonary arteries (RPA) and right ventricle (RV) remodeling. Rats were injected with saline or iron-dextran (10,...
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