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Novel therapeutic principles are urgently needed to cure inflammatory bowel diseases (IBD) that have been intrinsically linked to a deregulated inflammatory cytokine network. Here we identify the interleukin (IL)-1-like cytokine IL-33 and its receptor ST2 as novel negative regulators of wound healing in the colon of mice.Study in BL6 and IL-33R/ST2 deficient mice using dextran sodium sulfate (DSS)...
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