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The purpose of vascular disease screening is early identification of atherosclerotic disease and the aim of an ankle-brachial index (ABI) is to identify lower extremity (LE) atherosclerosis as a marker for coronary artery disease (CAD). However, early evidence of atherosclerosis may be present in the superficial femoral artery (SFA) with a normal resting ABI. This study was performed to determine...
Two cDNA clones, λ-CLFV-108 and λ-CLFV-119, encoding for the β-adrenergic receptor, have been isolated from a human brain stem cDNA library. One human genomic clone, LCV-517 (20 kb), was characterized by restriction mapping and partial sequencing. The human brain β-receptor consists of 413 amino acids with a calculated M r of 46 480. The gene contains three potential glucocorticoid receptor-binding...
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