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We describe a new label-free biosensor array chip developed for the real-time, simultaneous monitoring of multiple molecular binding reactions. It is composed of monolithically integrated grating couplers, microfluidic channels and spiral cavity silicon photonic wire sensors. The grating couplers use a novel design for coupling to the transverse magnetic mode of a silicon photonic wire. They contain...
A silicon waveguide evanescent field molecular sensor interrogated by reflection from a surface grating is demonstrated. The sensor is probed by a beam of light incident at thetas = 45deg through the backside of the silicon-on-insulator (SOI) wafer. The reflected power shows a strong resonant feature near lambda = 1532 nm, arising from resonant coupling of incident beam, guided mode, and the reflected...
We demonstrate a method of canceling the temperature dependence of ring resonator sensors using a double ring configuration. Temperature calibration curves are provided for SOI photonic wire ring sensors with air and SU8 polymer cladding.
Photonics is playing an increasingly important role in the field of medical diagnostics, genomics and drug discovery. With the advances in molecular biology which gives insight to the processes underlying diseases and drug response, there is a need for new biological sensors to rapidly detect and quantify these processes. Sensing of biological events using planar waveguide evanescent field (EVF) detection...
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