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The growing use of microparticles as a controlled-delivery system for pharmaceutical and non-pharmaceutical active ingredients (AIs) has prompted a costly trial-and-error development of new and effective microparticle systems. In order to facilitate a more rational design and optimization of AI loadings in microparticles, we have developed a molecular-thermodynamic theory to predict the loading of...
Tyrosine-derived polycarbonates are new carbonate-amide copolymers. These materials have been suggested for use in medical applications, but their thermal properties and their enthalpy relaxation kinetics (physical ageing behaviour) have so far not been evaluated in detail. Since structure-property correlations involving enthalpy relaxation are rarely investigated for biomedical polymers, a series...
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