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In the present study the role of 5-HT 3 receptors located at the medial septum/vertical limb of the diagonal band complex (MS/vDB) in the control of blood pressure in unanaesthetized rats was investigated. Microinjections of ondansetron, a selective 5-HT 3 receptor antagonist, into this area caused a dose-dependent increase in blood pressure. This rise was attenuated by the blockade...