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Alcohol abuse often co-exists with a major depressive disorder. In order to understand the development of this comorbidity, it is important to concentrate on the preceding process. It has been suggested that the link between alcohol use and depressive symptoms is a result of an interaction with genetic factors. The aim of this study was to longitudinally examine the effect of the 5-HTTLPR genotype...
Early onset of drinking among Dutch adolescents is highly prevalent. A lower age of onset is associated with several developmental and social risks.To evaluate the long-term effectiveness of two preventive interventions targeting heavy drinking in third-year high school students.Cluster RCT using four conditions for comparing two active interventions (separately and simultaneously) with a control...
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