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Response surface methodology using the Central Composite Rotatable Design (CCRD) model was used to optimize parameters for Acid Mine Drainage (AMD) remediation with shrimp and aquaculture farming waste (shrimp-shell and mussel byssus). The CCRD (23) consisting of three-factored factorial design with five levels was used in this study. The dependent variables were agitation, shrimp-shell and byssus...