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Hypercholesterolaemia and coronary artery disease have been shown to induce increased free-oxygen radicals and superoxides generation from endothelial cells as well as endo-thelial dysfunction. The investigation of the parallel changes in FOR and lipids concentrations during cholesterol-lowering therapy was the aim of the present study. Twenty patients, 13 men/7 women, mean age 53.2 + 9 years, with...
The influence of fluvastatin on coagulant-fibrinolytic system in patients with coronary artery disease were studied.Methods: Thirty patients with known coronary artery disease (M = 22, F = 8 mean age 52.4 ± 7.6 years) with primary hyperlipidemia (phenotype IIa, IIb) were studied.All patients were applied in a low lipid diet and 40 mg daily of fluvastatin were added for three months.Serum blood from...
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