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Treatments for Crohn’s disease (CD) have been linked to serious infections, malignancies, and dermatologic complications. We pooled and analyzed clinical trials of certolizumab pegol, a pegylated humanized Fab’ fragment against tumor necrosis factor, to quantify safety events in patients with CD.We collected data from 5 placebo-controlled trials, 9 open-label studies, and 1 dose-regimen study, conducted...
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