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The GABA A receptor is the main inhibitory receptor in the brain and its subunits originate from different genes or gene families (α1–α6, β1–β3, γ1–γ3, δ, ε, θ, π, or ρ1–3). In the mouse brain the anatomical distribution of GABA A receptor subunit mRNAs so far investigated is restricted to subunits forming benzodiazepine-sensitive receptor complexes (α1–α3, α5, β2, β3 and γ2) in the...
GABA A receptors are ligand-operated chloride channels assembled from five subunits in a heteropentameric manner. Using immunocytochemistry, we investigated the distribution of GABA A receptor subunits deriving from 13 different genes (α1-α6, β1-β3, γ1-γ3 and δ) in the adult rat brain. Subunit α1-, β1-, β2-, β3- and γ2-immunoreactivities were found throughout the brain, although differences...
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