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Sleep is disrupted in depressed subjects; it also deteriorates with age and with the transition to menopause. The nature of the interrelationship between mood, sleep, age and reproductive state is not well-defined.To evaluate the relationships between mood and sleep among healthy women in different reproductive states.We analyzed data from 11 young (20–26 years), 21 perimenopausal (43–51 years) and...
Progestins stimulate respiration. We have previously shown prolonged ventilatory improvement in chronic respiratory failure with short-term medroxyprogesterone acetate (MPA). The mechanism of the sustained respiratory effect is unknown. Insulin-like growth factor-I (IGF-I) and insulin have anabolic effects which could also improve ventilation in the long-term. To better understand the interactions...
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