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The tubular network of the tracheal system in the Drosophila embryo is created from a set of epithelial placodes by cell migration, rearrangements, fusions and shape changes. A designated number of cells is initially allocated to each branch of the system. We show here that the final cell number in the dorsal branches is not only determined by early patterning events and subsequent cell rearrangements...
Branching morphogenesis remodels epithelial tissues into tubular networks. This process is crucial to many organs, from the insect trachea to the vertebrate vasculature. Although Drosophila tracheal development has been well characterized morphologically and genetically, very little is known about the forces involved during morphogenesis. The repertoire of cell behaviors underlying tracheal primary...
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