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Background and aims. Hepatitis C virus infection is often associated with lymphoproliferative disorders such as essential mixed cryoglobulinemia and B-cell non-Hodgkin lymphoma, which show preferential expression of V H I family products. By analyzing immunoglobulin heavy chain usage, we addressed the question of whether or not clonal B-cell expansion occurrs in patients free of essential...
Introduction: One of the characteristics of tumor cells is the aberrant glycosylation of their surface proteins and lipids. Small and immaturely terminated O-glycans, like αGaINAc (the Tn antigen), αNeuNAc(2-6)αGaINAc (the S-Tn antigen), and βGal(1-3)αGaINAc (the T antigen), are frequently found to accumulate on the surface of adenocarcinomas. The aim of this study has been to investigate the T...
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