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Purpose: To define the maximum tolerated dose (MTD) and the nature of the toxicities associated with gemcitabine given as a short infusion to patients with non-small cell lung cancer (NSCLC). Secondary objectives were to monitor immunologic response, clinical response, and survival. Patients and methods: Thirty-two patients diagnosed with advanced inoperable NSCLC and performance status of 0 or 1...
Background. Lung reduction surgery is gaining acceptance in the treatment of patients suffering from severe diffuse emphysema. At the University of Pittsburgh 210 patients have been evaluated and 128 patients have undergone lung reduction operations. Methods. Ten patients, representing 7.8 % of the operated group, have had asymptomatic cancerous or neoplastic lesions diagnosed on preoperative...
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