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Osteoporosis is a common disorder characterized by reduced bone mineral density, deterioration of the microarchitecture of bone tissue and increased risk of fracture. The aim of treatment of osteoporosis is to maintain and, ideally, to restore bone strength safely. In recent years the role of polypeptide growth factors in bone metabolism has begun to appear. It has been proposed that alterations in...
Five analogues of Ala-Asp-Ser-Asp-Gly-Lys related to IgE with modifications at position 1,2 and 6 have been evaluated for antiallergic activity. One of the peptides (CDRI compound 94/335) was found to exhibit significant activity by oral route in rats.
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