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Association of HLA-Cw6 with psoriasis vulgaris (PV) is well known. Three amino acids, aspartic acid at position 9 (9Asp), alanine at position 73, and aspartic acid at position 90, which are found in HLA-Cw6, are hypothesized to play a role in susceptibility to PV. Among these amino acids, 9Asp located on B pocket of HLA molecule, which is the binding site of anchor amino acid in antigen peptides...