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We discuss a general notion of similarity function between two sequences which is based on their common subsequences. This notion arises in some applications of molecular biology [A.G. D'yachkov, P.L. Erdos, A.J. Macula, V.V. Rykov, D.C. Torney, C.-S. Tung, P.A. Vilenkin, and P.S. White, Exordium for DNA codes, Journal of Combinatorial Optimization 7 (4) (2003)]. We introduce the concept of similarity...
Single-nucleotide polymorphisms (SNPs) are the most abundant type of human genetic variation. These variable sites are present at high density in the genome, making them powerful tools for mapping and diagnosing disease-related alleles. We have developed a sensitive and rapid flow cytometry-based assay for the multiplexed analysis of SNPs based on polymerase-mediated primer extension, or minisequencing,...
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