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•DILIrank contains the largest number of drugs (N=1036) ranked by their risk for causing DILI.•The existing drug labeling-based DILI annotation was enhanced by weighing evidence of causality.•Drugs were classified as verified vMost-, vLess-, vNo-DILI-concern, leaving out terminology ‘Ambiguous DILI-concern’ drugs.•DILIrank is invaluable for the development of predictive models using emerging technologies...
In this study, we characterized the therapeutical effects of Salviae Mitiorrhizae (Danshen) and Cortex Moutan (Danpi) extract (SDD) on Sprague-Dawley rats subjected to coronary artery ligation, and applied proteomic approach to investigate its potential mechanism of action. The chemical composition of SDD was investigated by HPLC/MS n analysis. Measurement for serum levels of creatine kinase...
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