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Female Sprague Dawley rats were given a choice between two concentrations of nicotine solution (5 µg/ml and 8 µg/ml) and water in a 5-bottle arrangement for 25 days. Rats developed clear bottle discrimination, drinking more of the 5 µg/ml nicotine solution than water or the higher concentration nicotine solution. Further, intake patterns were sensitive to exposure. Differences in consumption of the...