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Key points
The ability to learn new motor skills is supported by plasticity in the structural and functional organisation of the primary motor cortex in the human brain.
Changes inhibitory to signalling by GABA are thought to be crucial in inducing motor cortex plasticity.
This study used magnetic resonance spectroscopy (MRS) to quantify the concentration of GABA in human motor cortex during a period...
Understanding both the organization of the human cortex and its relation to the performance of distinct functions is fundamental in neuroscience. The primary sensory cortices display topographic organization, whereby receptive fields follow a characteristic pattern, from tonotopy to retinotopy to somatotopy [1]. GABAergic signaling is vital to the maintenance of cortical receptive fields [2]; however,...
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