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We reported recently that immune complexes (ICs) induced matrix metalloproteinase-1 (MMP-1) expression in U937 histiocytes. The present study was undertaken to determine the effect of pretreatment of U937 cells with interferon-γ (IFN-γ) on IC-induced MMP-1 expression. Our flow cytometry studies showed that IFN-γ upregulated the surface expression of FcγRI, but not FcγRII. Results also showed that...