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Background The role of postoperative radiotherapy in breast-conserving therapy is undisputed. However, optimal timing of adjuvant radiotherapy is an issue of ongoing debate. This retrospective clinical cohort study was performed to investigate the impact of a delay in surgery–radiotherapy intervals on local control and overall survival. Patients and methods Data from an unselected cohort of 1393 patients...
Die Erkenntnisse der molekularen Onkologie im Hinblick auf die Mechanismen der Krebsentstehung und die Besonderheiten maligner Tumorzellen haben in der vergangenen Dekade zur Entwicklung einer Reihe neuer, zielgerichteter Ansätze zur Behandlung von Krebserkrankungen geführt. Diese adressieren gezielt Moleküle und Signalwege, die für das Überleben, die Proliferation und die Ausbreitung maligner Zellen...
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