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This trial was designed to determine the 1-year survival rate, efficacy, and safety, produced by topotecan and gemcitabine as first line chemotherapy in advanced non-small cell lung cancer (ANSCLC). Fifty-three patients were enrolled; 51 received treatment. Topotecan 1 mg/m 2 , days 1-5 and gemcitabine 1 g/m 2 days 1 and 15 were administered IV, each drug over 30 min; cycles consisted...
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