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We report the elaboration of new l-Proline functionalized superparamagnetic iron oxide nanoparticles that can act as a new enantioselective organocatalyst. Boc-l-Proline and Fmoc-l-Proline are grafted using two different methodologies on a nanoplateform constituted of 10nm maghemite (γ-Fe 2 O 3 ) nanoparticle stabilized by bidendate coating agent Alendronate. We show that coupling...
The metabolomic profiles of B16 melanoma cells were investigated in vitro with high resolution‐magic angle spinning proton magnetic resonance spectroscopy and OPLS multivariate statistical analyse. We compared the profiles for untreated melanoma B16‐F10 cells and Ca2+ chelating EGTA, doxorubicin or BP7033 bisphosphonate treated cells. The two last molecules are known to induce anti‐proliferative effects...
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