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Recent experimental evidence suggests that glial cells are more than just supporting cells to neurons — they play an active role in signal transmission in the brain. We herein propose to investigate the importance of these mechanisms and model neuron-glia interactions at synapses using three approaches: A parametric model that takes into account the underlying mechanisms of the physiological system,...
In this paper a 12 bits 50 kS/s micropower hybrid ADC is proposed for biomimetic microelectronic systems using 0.18 mum CMOS process. The hybrid ADC combines SAR and dual-slope architectures to achieve 12 bits, power consumption 60 muW, and small silicon die size. This hybrid ADC shows very good figure-of-merits (FOM) on both power consumption and silicon die size compared with conventional low power...
With the development toward an integrated single-chip multi-standard radio receiver, a DCR (direct conversion receiver) is usually preferable due to its low power consumption and low manufactory cost. Backward compatibility to narrow band standards such as GSM/EDGE is also important to avoid possible service interruption. However, the excess flicker noise in modern CMOS technology degrades the DCR...
Charge-metering microstimulator has been shown with higher charge accuracy, less charge-imbalance, and higher power efficiency than conventional current-mode and voltage-mode stimulators. In this paper, a discrete-time charge-metering microstimulator is proposed for implantable prosthetic device. Design techniques like half-clock sampling, high-voltage isolation, integration folding, and periodic...
A novel architecture to realize a low-power, low-noise amplifier for cortical neural prostheses is presented. The design consists of a low-noise variable gain amplifier as the first stage, a low-Gm high-pass filter as the second stage, and a low-pass Gm-C amplifier as the last stage. Discrete-time autozeroing is utilized to reduce the offset and noise. The bandwidth and autozeroing frequency of the...
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