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Reaction of 7-amino-3-[5′-methyl-1′,3′,4′-thiadiazol-2′-ylthiomethyl]cephalo-sporanic acid with heterocyclic amines using basic alumina under microwave irradiation (MWI) afforded new cephalosporin analogs in shorter reaction time with improved yield as compared to conventional heating. All the synthesised compounds were tested for their in vitro antibacterial activity, using cefotaxime and cephalothin...
New organomercurials of benzoquinone, barbituric acid and thiobarbituric acid with substituted aryl mercuric chloride have been synthesised using microwave irradiation under dry conditions in a domestic microwave oven in a few minutes with improved yields as compared to conventional heating. These organomercurials have a 1:1 stoichiometric ratio of aryl mercury and benzoquinone/barbituric acid/thiobarbituric...
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