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An immortal human hepatic cell line HL-7702 and human hepatoma cell line SMMC-7721 were treated with 3-30μM SeO 2 . SeO 2 at 30μM markedly inhibited cell proliferation and viability, and prompted apoptosis of both normal hepatic and hepatoma cells after 48h treatment. SeO 2 could also down-regulate the Bcl-2 level, greatly in HL-7702 and slightly in SMMC-7721 cells, but up-regulate...