Zhiquan Shu

article

H4S1ph, an alternative epigenetic marker for sperm maturity

Zhaohui Zhang, Shumei Mu, Tingrong Chen, Zhe Sun, more

Histone phosphorylation, an epigenetic post‐translational modification, plays essential roles in male gamete chromatin compaction during spermatogenesis and sperm maturity. Previously, we studied the epigenetic marker of phosphorylated serine 1 of histone H2A and H4 (HS1ph) during spermatogenesis in mice and crabs, which was shown to be closely related to the sperm maturity. To further investigate...

article

Investigation on the thermal performance of a novel microchannel-aided device for vitrification of cells/tissues

Xiaoming Zhou, Zhiquan Shu, Xin M. Liang, Chaojie Jiang, more

Applied Thermal Engineering > 2017 > 119 > C > 189-196

Among the cryopreservation technologies, vitrification has displayed significant advantages compared to the traditional methods. To obtain the desired cooling/rewarming rates for vitrification, recent approaches tend to minimize sample volume and thereby lower the inner thermal resistance. However, those approaches also lead to practical limitations in throughput and applicable sample types. To address...

article

Well-designed microcapsules fabricated using droplet-based microfluidic technique for controlled drug release

Zexia Luo, Gang Zhao, Fazil Panhwar, Mangrio Farhana Akbar, more

Journal of Drug Delivery Science and Technology > 2017 > 39 > Complete > 379-384

Microfluidics is an emerging technology for synthesis of drug-loaded micro- and nano capsules for targeted delivery and controlled release, which has extensive applications in tumor therapy and pharmacological study in healthcare. A number of polydimethylsiloxane (PDMS) microfluidic devices have been developed and widely used, while PDMS based microstructure device does not support long-term stability...

article

A study of the osmotic characteristics, water permeability, and cryoprotectant permeability of human vaginal immune cells

Zhiquan Shu, Sean M. Hughes, Cifeng Fang, Jinghua Huang, more

Cryobiology > 2016 > 72 > 2 > 93-99

Cryopreservation of specimens taken from the genital tract of women is important for studying mucosal immunity during HIV prevention trials. However, it is unclear whether the current, empirically developed cryopreservation procedures for peripheral blood cells are also ideal for genital specimens. The optimal cryopreservation protocol depends on the cryobiological features of the cells. Thus, we...

article

Effect of iron oxide nanoparticles on the permeability properties of Sf21 cells

Jianye Wang, Gang Zhao, Zhiquan Shu, Ping Zhou, more

Cryobiology > 2016 > 72 > 1 > 21-26

It was recently reported that nanoparticles could significantly modulate the thermal properties of solutions at subzero temperatures, and as a result, nanoparticles have been widely used in both cryopreservation and cryosurgery. In cryopreservation, the water permeability coefficient of cell membrane is an essential parameter for quantitative investigation of cell dehydration and intracellular ice...

article

Permeation kinetics of dimethyl sulfoxide in human vaginal mucosal tissues

Zhiquan Shu, Sean M. Hughes, Cifeng Fang, Jiaji Pan, more

Cryobiology > 2015 > 71 > 3 > 559

article

High-precision approach based on microfluidic perfusion chamber for quantitative analysis of biophysical properties of cell membrane

Wei Liu, Gang Zhao, Zhiquan Shu, Tao Wang, more

International Journal of Heat and Mass Transfer > 2015 > 86 > C > 869-879

Cell membrane permeability, one of the key biophysical properties of cells, plays an important role in bioengineering, regenerative medicine, tissue engineering, and biopreservation and biobanking. One featured and cell specific approach has been well established by the cryobiologists for determination of cell membrane permeability, i.e., osmotic shift experiments utilizing perfusion microchamber...

article

Application of hydrogel in cryopreservation as a novel cryoprotectant, encapsulation and single-cell-based functional sensing material

Zhiquan Shu, Wanyu Chen, Amy Q. Shen, Dayong Gao

Cryobiology > 2014 > 69 > 3 > 506

Some challenges still remain in cryopreservation and cytotherapy, including (1) cryoinjury due to intracellular ice formation may cause cell loss during cryopreservation. Non-freezing preservation may be achieved by vitrification with ultra-high cooling rate or cryoprotectant concentration; however, this is unfeasible or cytotoxic. (2) Immune rejection response may happen to the transplanted cell...

article

Biotransport and intracellular ice formation phenomena in freezing human embryonic kidney cells (HEK293T)

Yunpeng Xu, Gang Zhao, Xiaoming Zhou, Weiping Ding, more

Cryobiology > 2014 > 68 > 2 > 294-302

The objective of this study is to determine the cryobiological characteristics of human embryonic kidney (HEK293T) cells. The cell membrane hydraulic conductivity (L _pg ) and the activation energy of water transport (E _Lp ) were determined in the absence/presence of cryoprotectant agent (CPA), while the nucleation rate kinetic and thermodynamic parameters (ΩoSCN and κoSCN) were determined...

article

Theoretical investigations of a novel microfluidic cooling/warming system for cell vitrification cryopreservation

Xiaoming Zhou, Zhong Liu, Xin M. Liang, Zhiquan Shu, more

International Journal of Heat and Mass Transfer > 2013 > 65 > Complete > 381-388

Ultra-fast cooling and rewarming are essential to vitrification cryopreservation. In this work the existing cooling/warming approaches are reviewed and then a novel microfluidic system is proposed. The main concerns of the design includes: (a) enhancing the external heat transfer coefficients by utilizing micro-channel array on the chip surface; (b) increasing the sample surface versus its volume...

article

Microfabricated thermal conductivity sensor: a high resolution tool for quantitative thermal property measurement of biomaterials and solutions

Xin M. Liang, Weiping Ding, Hsiu-hung Chen, Zhiquan Shu, more

Biomedical Microdevices > 2011 > 13 > 5 > 923-928

Obtaining accurate thermal properties of biomaterials plays an important role in the field of cryobiology. Currently, thermal needle, which is constructed by enclosing a manually winded thin metal wire with an insulation coating in a metallic sheath, is the only available device that is capable of measuring thermal conductivity of biomaterials. Major drawbacks, such as macroscale sensor size, lack...

article

The Structural and Cellular Viability in Cryopreserved Rabbit Carotid Arteries1 1 This work was supported by the Natural Science Funding of China (NSFC59976041) and the Hundred-Talent Award of CAS (2001–2003).

Peitao Wang, Zhiquan Shu, Liqun He, Shuxia Chen, more

Journal of Surgical Research > 2006 > 131 > 2 > 241-251

We investigated the histological and mechanical changes in addition to viable cellular recovery in cryopreserved blood vessels. Rabbit carotids were cryopreserved in a cryoprotective medium containing 1.5 M of 1,2-propanediol (PD) and then were thawed slowly in an ice bag that had been precooled in liquid nitrogen. Fresh carotids were used as the control. The fresh and freeze-thawed arteries were...

article

Double porous media model for mass transfer of hemodialyzers

Weiping Ding, Liqun He, Gang Zhao, Haifeng Zhang, more

International Journal of Heat and Mass Transfer > 2004 > 47 > 22 > 4849-4855

Double porous media model for mass transfer of hollow fiber hemodialyzers is presented. In the model, the hollow fiber bundle is treated as a porous region composed of two interpenetrating porous regions i.e. the blood and dialysate flow regions, and the interface of the two regions is the porous membrane through which mass transfer is performed. Navier-Stokes equations with Darcy source terms are...

article

Determination of cell volume during equilibrium freezing process

Gang Zhao, Liqun He, Peitao Wang, Weiping Ding, more

Chinese Science Bulletin > 2003 > 48 > 15 > 1551-1554

A new type electronic particle counter (EPC, Multisizer^tm 3, Beckman Coulter Inc., USA) was used to determine the volumes of human red blood cells (RBCs) in NaCl solutions of different osmolalities. The thermodynamics model describing cell response during freezing process was used to simulate the volume change of RBC in 0.9% NaCl solution during equilibrium freezing process. It was assumed that the...

article

A novel theoretical model for mass transfer of hollow fiber hemodialyzers

Weiping Ding, Liqun He, Gang Zhao, Zhiquan Shu, more

Chinese Science Bulletin > 2003 > 48 > 21 > 2386-2390

A novel theoretical model for mass transfer of hollow fiber bundles in hemodialyzers is presented. In the model, a hemodialyzer is considered as a porous zone which is composed of two non-interpenetrating porous flow zones. Firstly, the dialysate side (shell side) is thought as a porous medium zone. Then by solidifying the dialysate flow zone and the occupied zone by hollow fiber membrane, the rest...

INFONA - science communication portal

Search results for: Zhiquan Shu

H4S1ph, an alternative epigenetic marker for sperm maturity

Investigation on the thermal performance of a novel microchannel-aided device for vitrification of cells/tissues

Well-designed microcapsules fabricated using droplet-based microfluidic technique for controlled drug release

A study of the osmotic characteristics, water permeability, and cryoprotectant permeability of human vaginal immune cells

Effect of iron oxide nanoparticles on the permeability properties of Sf21 cells

Permeation kinetics of dimethyl sulfoxide in human vaginal mucosal tissues

High-precision approach based on microfluidic perfusion chamber for quantitative analysis of biophysical properties of cell membrane

Application of hydrogel in cryopreservation as a novel cryoprotectant, encapsulation and single-cell-based functional sensing material

Biotransport and intracellular ice formation phenomena in freezing human embryonic kidney cells (HEK293T)

Theoretical investigations of a novel microfluidic cooling/warming system for cell vitrification cryopreservation

Microfabricated thermal conductivity sensor: a high resolution tool for quantitative thermal property measurement of biomaterials and solutions

The Structural and Cellular Viability in Cryopreserved Rabbit Carotid Arteries1 1 This work was supported by the Natural Science Funding of China (NSFC59976041) and the Hundred-Talent Award of CAS (2001–2003).

Double porous media model for mass transfer of hemodialyzers

Determination of cell volume during equilibrium freezing process

A novel theoretical model for mass transfer of hollow fiber hemodialyzers

Filter options

Publication date

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Zhiquan Shu

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options