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Computational models of myocardial ischemia often use oversimplified ischemic source representations to simulate epicardial potentials. The purpose of this study was to explore the influence of biophysically justified, subject-specific ischemic zone representations on epicardial potentials.We developed and implemented an image-based simulation pipeline, using intramural recordings from a canine experimental...
In the quest for patient specific models for predicting defibrillation efficacy, one of the questions is which tissue types to include into a volume conductor model of the torso. We present a comparison between a model consisting of 11 different tissue types to models with only a subset of of tissue types across a database of electrode orientations including transvenous, epicardial, and subcutaneous...
The performance of back-propagation artificial neural networks (NN) and partial least squares (PLS) regression for the calibration of linear and nonlinear systems has been investigated by using six types of synthetic data. Three PLS methods, conventional linear-PLS and two nonlinear-PLS methods, have been used in the study. In all but one of the synthetic data types, the band intensities varied nonlinearly...
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