David L. DeFoe

article

Evaluation of the Model Anti-androgen Flutamide for Assessing the Mechanistic Basis of Responses to an Androgen in the Fathead Minnow ( Pimephales promelas )

Gerald T. Ankley, David L. Defoe, Michael D. Kahl, Kathleen M. Jensen, more

Environmental Science & Technology > 2004 > 38 > 23 > 6322 - 6327

article

Evaluation of time-to-effects as a basis for quantifying the toxicity of contaminated sediments

David L. DeFoe, Gerald T. Ankley

Chemosphere > 2003 > 51 > 1 > 1-5

Due to uncertainties as to appropriate procedures and dilution materials, most sediment tests are conducted only with undiluted, whole samples. Hence, it is not possible to use conventional concentration-response approaches to quantify toxicity of samples that elicit a 100% effect (e.g., mortality) at a preset test interval (typically 10 d). An alternative approach to quantifying the relative toxicity...

article

Assessment of the Risk of Solar Ultraviolet Radiation to Amphibians. I. Dose-Dependent Induction of Hindlimb Malformations in the Northern Leopard Frog ( Rana pipiens )

Gerald T. Ankley, Stephen A. Diamond, Joseph E. Tietge, Gary W. Holcombe, more

Environmental Science & Technology > 2002 > 36 > 13 > 2853 - 2858

article

Saturation units for use in aquatic bioassays

Michael D. Kahl, Christine L. Russom, David L. DeFoe, Dean E. Hammermeister

Chemosphere > 1999 > 39 > 3 > 539-551

Methods were developed for preparing liquid/liquid and glass wool column saturators for generating chemical stock solutions for conducting aquatic bioassays. Exposures have been conducted using several species of fish, invertebrate, and mollusks in static and flow-through conditions using these methods. Stock solutions for 82 organic chemicals were prepared using these saturation units. The primary...

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Additive Toxicity of Binary Mixtures of Phototoxic Polycyclic Aromatic Hydrocarbons to the OligochaeteLumbriculus variegatus

Russell J. Erickson, Gerald T. Ankley, David L. DeFoe, Patricia A. Kosian, more

Toxicology and Applied Pharmacology > 1999 > 154 > 1 > 97-105

Toxicity of some polycyclic aromatic hydrocarbons (PAHs) can increase by an order of magnitude, or more, in the presence of solar ultraviolet (UV) radiation. In the environment, PAHs exist as complex mixtures, which generally would include multiple PAHs that could cause photoinduced toxicity. Hence, to accurately predict the potential ecological risk of phototoxic PAHs, it is critical to understand...

article

Influence of storage time on toxicity of freshwater sediments to benthic macroinvertebrates

David L. DeFoe, Gerald T. Ankley

Environmental Pollution > 1998 > 99 > 1 > 123-131

Guidance concerning recommended storage times for sediments to be used in toxicity tests generally has not been based upon systematically collected experimental data. The objective of this study was to better define the effects of storage time on toxicity of a series of freshwater sediments. Sixteen sediments with varying types of contaminants were collected, homogenized and stored at 4°C in 1 liter...

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Search results for: David L. DeFoe

Evaluation of the Model Anti-androgen Flutamide for Assessing the Mechanistic Basis of Responses to an Androgen in the Fathead Minnow ( Pimephales promelas )

Evaluation of time-to-effects as a basis for quantifying the toxicity of contaminated sediments

Assessment of the Risk of Solar Ultraviolet Radiation to Amphibians. I. Dose-Dependent Induction of Hindlimb Malformations in the Northern Leopard Frog ( Rana pipiens )

Saturation units for use in aquatic bioassays

Additive Toxicity of Binary Mixtures of Phototoxic Polycyclic Aromatic Hydrocarbons to the OligochaeteLumbriculus variegatus

Influence of storage time on toxicity of freshwater sediments to benthic macroinvertebrates

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INFONA - science communication portal

Search results for: David L. DeFoe

Evaluation of the Model Anti-androgen Flutamide for Assessing the Mechanistic Basis of Responses to an Androgen in the Fathead Minnow ( Pimephales promelas )

Evaluation of time-to-effects as a basis for quantifying the toxicity of contaminated sediments

Assessment of the Risk of Solar Ultraviolet Radiation to Amphibians. I. Dose-Dependent Induction of Hindlimb Malformations in the Northern Leopard Frog ( Rana pipiens )

Saturation units for use in aquatic bioassays

Additive Toxicity of Binary Mixtures of Phototoxic Polycyclic Aromatic Hydrocarbons to the OligochaeteLumbriculus variegatus

Influence of storage time on toxicity of freshwater sediments to benthic macroinvertebrates

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