The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
INTRODUCTION: The amygdala mediates unconscious reactions and is responsible for emotional memory formation and attachment of subjective emotional valence to various stimuli. The amygdala complex expresses 5-HT7 receptors in a high density, however, their function in this structure remains poorly investigated. AIM(S): The present experiments were aimed at determining the effects of 5-HT7 receptor...
The amygdala is a part of the limbic system involved in emotional processing, which is highly connected with other areas of the brain. Its basolateral region (BLA) re‑ ceives many inputs, including those from prefrontal cor‑ tex, hippocampus, and thalamus. Moreover, the amygdala receives robust innervation from the raphe nuclei. The last serotonin receptor to be discovered, 5-HT7, is highly expressed...
The 5‑HT7 receptor has been implicated in mood reg‑ ulation, circadian rhythmicity, and sleep, the disturbances of which are evident in the course of depressive disorders. Research into 5‑HT7 receptor signalling in the hippocam‑ pus has indicated that activation of the 5‑HT7 receptor increases the excitability of pyramidal neurons of the CA1 and CA3 areas. The aim of our study was to investigate ionic...
The 5-HT7 receptor is one of the several serotonin (5-HT) receptor subtypes that are expressed in the dorsal raphe nucleus (DRN). Some earlier findings suggested that 5-HT7 receptors in the DRN are localized on the GABAergic interneurons and glutamatergic terminals which modulate the activity of 5-HT DRN projection neurons. The present study was aimed at finding how the 5‑HT7 receptor modulates the...
Over the last few years OneM2M global initiative has been working on creation of global specification and standards for M2M. In order to facilitate the development of future M2M applications, which will be consolidated with this M2M standard, this paper compares OneM2M standard with ETSI M2M standard, which was defined by European Telecommunications Standards Institute, and presents ETSI M2M and OneM2M...
BACKGROUND AND AIMS: The 5-HT7 receptor is one of the several 5-HT receptor subtypes which are expressed in DRN neurons. Some previous findings suggested that 5-HT7 receptors in the DRN are localized on local GABAergic interneurons, which modulate the activity of 5-HT projection neurons. The aims of this study were to determine how the 5-HT7 receptor activation and blockade influence the GABAergic...
BACKGROUND AND AIMS: The hypothalamic paraventricular nucleus (PVN) plays a key role in the activation of the hypothalamic-pituitary-adrenal axis (HPA). In response to stress, corticotropin releasing hormone (CRH) is released from parvocellular PVN neurosecretory neurons into hypophysial portal vessels that access the anterior pituitary gland to stimulate the production of the adrenocorticotropic...
Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new, efficient way to achieve antipsychotic-like effects. Such an activity was shown for mGlu2/3 and mGlu5 receptor agonists/positive modulators, as well as for ACPT-I or LSP1-2111, a non-selective mGlu group III receptors orthosteric agonists. Herein, we report the pharmacological...
The hypothalamic paraventricular nucleus (PVN) plays a key role in the activation of the hypothalamic-pituitary-adrenal axis (HPA) in response to stressors. Wistar rats were subjected to restraint lasting 10 min and repeated twice daily for 3 days. Brain slices were prepared 24 h after the last restraint session and studied ex vivo. Whole-cell patch-clamp method was used to record spontaneous excitatory...
The paraventricular nucleus of the hypothalamus (PVN) is the main regulatory center of the hypothalamic-pituitary-adrenal (HPA) axis. One important function of PVN neurosecretory neurons is the release of corticotropin releasing hormone (CRH) to the pituitary gland. This study was aimed at establishing the effects of restraint stress on GABAergic and glutamatergic inputs to parvocellular neurons of...
It has been estimated that by the end of 2020 there will be 50 billion connected devices world-wide. Such projections entice the industry to explore and tap a wide range of opportunities that the M2M (Machine-to-Machine) communication concept offers, enabling novel business cases, enhanced workflow efficiency and improved quality of life. It is therefore no surprise that prominent telecommunication...
Chronic stress and resulting from it, prolonged hyperactivation of the hypothalamic–pituitary–adrenal (HPA) axis and elevated level of glucocorticoids in the circulatory system, have been linked to the pathophysiology of depressive disorders. Dysregulation of the HPA axix is characteristic for individuals with depression. The paraventricular nucleus of the hypothalamus (PVN) is a major regulator of...
Hippocampal GABAergic interneurons modulate the activity of principal glutamatergic cells. Hippocampus receives 5-HT innervation originating in raphe nuclei. In this study we aimed at establishing whether the 5-HT7 receptor-dependent modulation of hippocampal functions also involves local inhibitory circuits. We investigated the effects of 5-HT7 receptor activation on the glutamatergic input to stratum...
In order to increase profit and remain competitive on the telecommunication market, telcos must introduce new types of services. Nowadays, basic mobile services are insufficient for an average user: advanced services include combination of entertainment and information content, and as such require greater personalization. The future of mobile communications is directed towards creating systems aware...
Peer-to-Peer systems (P2P) are getting increasingly popular as an efficient way of sharing any kind of data, and they are wide accepted in world of computing. In world of small devices (e.g. Smartphones, PDAs) P2P systems are not widespread yet, due to limitation when considering mobile device connection requirements. However, P2P system could decrease usage of bandwidth for group of users who are...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.