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Rift Valley fever (RVF) poses a risk as a potential agent in bioterrorism or agroterrorism. A live attenuated RVF vaccine (RVF MP-12) has been shown to be safe and protective in animals and showed promise in two initial clinical trials. In the present study, healthy adult human volunteers (N=56) received a single injection of (a) RVF MP-12, administered subcutaneously (SQ) at a concentration of 10...
The flexible grinding tools with polyurethane bonds create the distinct group of grinding tools from their specific properties. This properties cause that the vertical displacement of grinding grains can obtain one millimeter values in the polishing process of flat surfaces. This article presents the methodology of experimental research the contact deflections of individual grinding grains which are...
In engineering applications, stereometric characteristics of rough surfaces are described using parameters of single profile, for example assuming that average height of profile vertexes is the same as everage height of profile vertexes of surface. These characteristics are often different, what causes non adequacy of such a form of surface description. Probability of fact, that vertex of surface...
The shaping of surface in precision machining requires does not large caving of blade in workpiece- microcutting process. This article presents the analysis of microcutting processes with grains located on flexible carrier with consideration of typical quality of flexible grinding tools, which is the local interaction between the adjacent grains during polishing machining. The new conceptions of forming...
Purpose: Nonendoscopic, fluoroscopic biopsy of the gastric mucosa, following barium examination of the stomach, has gained attention with its ease of performance and cost savings potential over endoscopy. Endoscopic research concerning the efficacy of biopsy sites has revealed an increased sensitivity of antral biopsies over greater curvature biopsies for the detection of Helicobacter pylori. Fluoroscopically...
A purified monovalent botulinum type F toxoid vaccine was administered to 35 healthy adult volunteers in a phase I clinical trial. Serum samples from the vaccinated volunteers were evaluated for an antibody response at various time intervals over 1 year by mouse bioassay and ELISA. The antibody response was measured for varying doses of vaccine (2, 5, or 10 μg), and after single or multiple (two or...
The US Army successfully developed a live-attenuated Venezuelan Equine Encephalitis (VEE) vaccine, TC-83, in 1961, and subsequently developed a formalin-inactivated vaccine, C-84, in 1974. Initial evaluation of both vaccines was promising, but no long-term safety and immunogenicity data have been reported. This study is the first analysis of the long-term safety and immunogenicity of TC-83 and C-84...
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