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Cessation of blood flow in tissues leads to depletion of energetic resources of cells, disturbances in the activity of enzymes of the oxidative chain and electrolyte disorders, as well as to the production of reactive oxygen species. A great deal of attention has been paid to those problems since they are responsible for most of the complications in the ischemia-reperfusion (I/R) syndrome. Understanding...
Acute ischemia and the subsequent reperfusion caused by temporary closure of blood flow in the main arteries, which activate generalized inflammatory response, lead to endothelial injury. The aim of the study was to examine the injury of tissues in the ischemia reperfusion syndrome. Additionally, we tried to estimate the role of B1 and B2 bradykinin-receptor antagonists. In our study we histologically...
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