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The aim of this lecture is to find a bridge between a current understanding of early events during oncogenesis and the complexity of cancer disease, whose development and course is a consequence of interactions on various levels, local as well as systemic between cancer cells and cellular components of patients surveillance and homeostasisi systems.
The combination of one dose of the cytostatic agent (bromoanalog of ifosfamide) administration with subsequent peritumoral injections of the cytokine-producing cells was observed to be more efficient in the tumor growth inhibition as compared with the cytostatic alone.
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