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Despite the great variability of the conus peptides characterized until now only relatively few have been identified that interact with K + channels. κM-conotoxin RIIIK (κM-RIIIK) is a 24 amino acid peptide from Conus radiatus, which is structurally similar to μ-conotoxin GIIIA, a peptide known to block specifically skeletal muscle Na + channels. Recently, it has been shown that κM-RIIIK...
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