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Ion channels lie at the interface between two areas of science: as physiological relays in biology and as picoampere/millivolt conductors in physics. It is precisely the complementarity of these two worlds which led to the emergence of the novel patch-clamp technique. By providing direct access to the activity of the protein channel, the patch clamp brought about a revolution in the molecular scale...
The detection of human antibodies of Multiple Sclerosis patients was investigated based on the electrochemical oxidation of a synthetic antigenic probe, a glycopeptide Fc-CSF114(Glc) bearing a ferrocenyl moiety. Electrochemical measurements were carried out at platinum microband electrodes without any electrode surface modification. A microfluidic device was designed in order to both minimize peptide...
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