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Brain atrophy is one of the parameters considered by experts for rating dementia from neuro-imaging findings. Research efforts have focused on measuring brain atrophy from images through experts' visual assessment or computer-based approaches. However, agreement between the visual assessment and computer-based measurement of atrophy is not yet investigated. Accordingly, this paper presents an automated...
An application of content-based image retrieval is proposed for identifying plants, along with a preliminary implementation. The system takes a plant image as input and finds the matching plant from a plant image database and is intended to provide users a simple method to locate information about their house plants. Max-flow min-cut technique is used as the image segmentation method to extract the...
IVUS-derived virtual histology (VH) permits the assessment of atherosclerotic plaque morphology by using radiofrequency analysis of ultrasound signals. However, it requires the acquisition to be ECG-gated, which is a major limitation of VH. Indeed, its computation can only be performed once per cardiac cycle, which significantly decreases the longitudinal resolution of VH. To overcome this limitation,...
We present a new active contour-based, statistical method for simultaneous volumetric segmentation of multiple subcortical structures in the brain. Neighboring anatomical structures in the human brain exhibit co-dependencies which can aid in segmentation, if properly analyzed and modeled. Motivated by this observation, we formulate the segmentation problem as a maximum a posteriori estimation problem,...
Registration of multiple medical images is required for analysis of both pathological and normal anatomical human body structures. In this study, we defined and automatically detected some anatomical landmarks which are considered to be unaffected from brain deformation such as symmetry axis of brain, nose tips, eye ball centers, and location of center of masses of certain slices. Registration is...
In this paper, we present a 3D shape modeling method using a statistical shape analysis framework, for design of implants and prosthetic devices customized to a patient's anatomy. We present a novel method to learn the relationship between two classes of shapes, which are related by certain operations or transformation. The two associated shape classes are represented in a lower dimensional manifold,...
This paper presents a new method for multiple structure segmentation, using a maximum a posteriori (MAP) estimation framework, based on prior shape densities involving nonparametric multivariate kernel density estimation of multiple shapes. Our method is motivated by the observation that neighboring or coupling structures in medical images generate configurations and co-dependencies which could potentially...
We present a novel method to track a guidewire in cardiac X-ray video. Using variational calculus, we derive differential equations that deform a spline, subject to intrinsic and extrinsic forces, so that it matches the image data, remains smooth, and preserves an a priori length. We analytically derive these equations from first principles, and show how they include tangential terms, which we include...
This paper presents a new approach for segmentation of multiple brain structures. We introduce a new coupled shape prior for neighboring structures in magnetic resonance images (MRI) for multi object segmentation problem, where the information obtained from images can not provide enough contrast or exact boundary. In segmentation of low contrasted brain structures we take the advantage of using prior...
An uncooled thermal detector array with low NETD is designed and fabricated using MEMS bimaterial structures. A diffraction grating is embedded on the pixel membrane for sensing sub-nm mechanical deflections. The first order reflected light was focused on a CCD camera to monitor the entire array. Results show that it is possible to achieve < 50mK NETD using a 12 bit CCD camera.
Several studies dealt with medical ultrasound registration. Their similarity metrics relied on pixel-to-pixel intensity comparisons. Hence, they are not well suited to the case of speckled images. To better handle the speckle noise, our previous work proposed an information-theoretic feature detector-based registration approach. This work aims to extend it to the cases where the image speckle model...
In this paper we derive differential equations for evolving radial basis functions (RBFs) to solve segmentation problems. The differential equations result from applying variational calculus to energy functionals designed for image segmentation. Our methodology supports evolution of all parameters of each RBF, including its position, weight, orientation, and anisotropy, if present. Our framework is...
Accurate staging of nodal cancer still relies on surgical exploration because many primary malignancies spread via lymphatic dissemination. The purpose of this study was to utilize nanoparticle-enhanced lymphotropic magnetic resonance imaging (LN-MRI) to explore semi-automated noninvasive nodal cancer staging. We present a joint image segmentation and registration approach, which makes use of the...
The detection of image features is an essential component of medical image processing, and has wide-ranging applications including adaptive filtering, segmentation, and registration. In this paper, we present an information-theoretic approach to feature detection in ultrasound images. Ultrasound images are corrupted by speckle noise, which is a disruptive random pattern that obscures the features...
We present a registration framework based on feature points of anatomical, 3D shapes represented in the point cloud domain. Anatomical information is utilized throughout the complete registration process. The surfaces, which in this paper are ear impression models, are considered to be similar in the way that they possess the same anatomical regions but with varying geometry. First, in a shape analysis...
This paper presents a fast and efficient method to determine intervertebral disk orientation in a magnetic resonance (MR) image of the spine. The algorithm originates from active contour theory and enforces a shape constraint to avoid leaks through weak or non-existent boundaries. The method represents a vertebra as a rectangle, modeled as a semi-affine transformation applied to the unit square. A...
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