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The new alleles human leukocyte antigen (HLA)‐B*40:122 and HLA‐B*40:127 differs from B*40:02:01 and B*40:06:01:01 by a single nucleotide, respectively.
The new human leukocyte antigen (HLA) class I allele, HLA‐Cw*0134, was identified in a Chinese individual. HLA‐Cw*0134 differs from HLA‐Cw*0124 by one nonsynonymous nucleotide change at the codon 99 (TGT to TAT) and one synonymous nucleotide change at the codon 127 (AAC to AAT).
Abstract
Down‐regulated expression of human leukocyte antigen (HLA) class I molecules in many human cancers facilitate tumor cells to escape from immune attack. Promoter hypermethylation, one of the major epigenetic changes responsible for gene inactivation, plays an important role in gastric carcinogenesis. This study evaluated the expression and alteration of HLA class I molecules in a panel of...
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